Kallol Gupta

This paper introduces DNA nanorings to dynamically control membrane tension in sub-100 nm liposomes, enabling controlled mechanical stress and molecular cargo release.

This paper uses native mass spectrometry to show BTK recruits to membranes via phosphatidylserine and is activated by PIP3, proposing a two-step mechanism for membrane recruitment and activation.

This study investigates the structure and function of human Xkr4, showing it scrambles lipids and adopts a novel conformation that promotes membrane thinning, essential for phosphatidylserine externalization.

The paper shows that DDHD2 is essential for neurons to use fatty acids from lipid droplets as an energy source during activity when glucose is unavailable.

This paper introduces a platform for high-throughput extraction of membrane proteins into native nanodiscs while preserving their local membrane context and provides a database for optimized extraction conditions.

The paper reconstitutes core synaptic machinery to reveal DAG's role in vesicle priming and Ca2+-triggered release, showing DAG accelerates SNAREpin assembly and affects release dynamics.