Author

Simon T. Herrmann

Leibniz Institute of Virology (LIV)ORCID 0009-0007-1438-3654Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Assay:proteomics· 1

Frequent Co-Authors

Natalie HeineniD· 2 shared Stephanie PfaenderiD· 2 shared Alexander RiekiD· 1 shared Amelie Schreieck· 1 shared Angele BreithauptiD· 1 shared Anne Balkema‐BuschmanniD· 1 shared Antje DickmannsiD· 1 shared Barbara SitekiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersMicrobiology

Natalie HeinenORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintAug 26, 2026

Quantitative modeling of SARS-CoV-2 replication reveals phase-specific bottlenecks and antiviral targets

Simon T. Herrmann, Timon Kapischke, Saskia Westhoven…·Lars Kaderali

The paper models SARS-CoV-2 replication dynamics in human cells, identifies key bottlenecks, and evaluates antiviral drug effects using mathematical modeling and experimental data.

DOI 10.64898/2026.06.23.733955

humanbulk RNA-seq

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Molecular BiologybioRxivPreprintJun 28, 2021

N4-hydroxycytidine and inhibitors of dihydroorotate dehydrogenase synergistically suppress SARS-CoV-2 replication

Kim M. Stegmann, Antje Dickmanns, Natalie Heinen…·Matthias Dobbelstein

This paper shows that combining N4-hydroxycytidine and DHODH inhibitors strongly reduces SARS-CoV-2 replication in cell cultures.

8 citations

experimental assay

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