Antje Dickmanns

This study shows that combining Nirmatrelvir with GRP78 inhibitors strongly reduces SARS-CoV-2 replication in vitro and in a hamster model.

This paper shows that combining N4-hydroxycytidine with CTP synthetase inhibitors strongly reduces SARS-CoV-2 replication in cell culture and animal models.

This paper shows that DHODH inhibitors enhance the antiviral effect of 4'-FlU against multiple RNA viruses, including influenza, SARS-CoV-2, and Ebola virus.

This paper shows that combining N4-hydroxycytidine and DHODH inhibitors strongly reduces SARS-CoV-2 replication in cell cultures.

This paper shows that methotrexate inhibits SARS-CoV-2 replication in cell cultures and synergizes with remdesivir, suggesting potential for repurposing MTX in treating COVID-19.