Author

Timothy B. Simmons

University of Tennessee at KnoxvilleORCID 0009-0007-2208-1920Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:ATAC-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:Hi-C· 1

Frequent Co-Authors

Alyssa E. Ward· 1 shared Amanda Swets· 1 shared Amit S. JoshiiD· 1 shared Amita Rani SahooiD· 1 shared Christopher PlayteriD· 1 shared Francisco N. BarreraiD· 1 shared Ioannis SgouralisiD· 1 shared Jennifer A. RybakiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Alyssa E. Ward

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2 papers

Recent·Most cited

Cell BiologyMolecular Biology of the CellPeer-reviewedSep 9, 2026

Reversibility of Nuclear and 3D Genomic Changes in Non-Cancerous Fibroblasts After Constricted Migration

Christopher Playter, Samuel John Benson, Renata Dos Reis Marques…·Rachel Patton McCord

This study shows that non-cancerous fibroblasts experience reversible nuclear and 3D genomic changes after constricted migration, unlike stable changes in cancer cells.

DOI 10.1091/mbc.e26-01-0053

humanATAC-seq

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BiochemistryCommunications BiologyPeer-reviewedMar 11, 2025

Cholesterol inhibits oncogenic EphA2 activation

Ryan J Schuck, Alyssa E. Ward, Amita Rani Sahoo…·Francisco N. Barrera

This study shows that cholesterol inhibits EphA2 self-assembly and oncogenic signaling by preventing its activation through an in-trans mechanism involving protein kinase A.

13 citations

humanproteomics

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