Author

Emily M. Meara

Brigham and Women's HospitalORCID 0009-0007-2643-8413Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1 Approach:transformer / foundation model· 1

Frequent Co-Authors

Andrew C. KruseiD· 2 shared Jeffrey S. SmithiD· 2 shared Abigail GilmeriD· 1 shared Alyana J. GranadosiD· 1 shared Andrew N. DatesiD· 1 shared Ari S. HilibrandiD· 1 shared Chanpreet JassaliD· 1 shared Claudia Y. LeeiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

Andrew C. KruseORCID

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2 papers

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedJul 17, 2026

β-arrestin recruitment facilitates a direct association with G proteins

Claudia Y. Lee, Jeffrey S. Smith, Taylor Kohlmann…·Sudarshan Rajagopal

This study shows that G proteins and β-arrestins can directly interact, with Gi family members differing in their association with β-arrestin, and this selectivity is located in the alpha helical domain of Gi.

DOI 10.1038/s41467-026-74944-7

experimental assaycell signaling & trafficking

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BiochemistryNature CommunicationsPeer-reviewedApr 23, 2026

In silico discovery of nanobody binders to a G-protein coupled receptor using AlphaFold-Multimer

Edward P. Harvey, Jeffrey S. Smith, Joseph D. Hurley…·Katherine J. Susa

The paper uses AlphaFold-Multimer to predict nanobody binders to MRGPRX2, demonstrating in silico antibody discovery for a GPCR target.

7 citationstop 1%

humanprotein structure

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