Author

Sean Krivitsky

Cold Spring Harbor LaboratoryORCID 0009-0007-3376-2940Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Christy Felice· 1 shared David L. SpectoriD· 1 shared Douglas T. FearoniD· 1 shared Jordan A. PearsoniD· 1 shared Jung‐In YangiD· 1 shared Maria C. PanepintoiD· 1 shared Nicholas K. TonksiD· 1 shared Paolo CifaniiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Christy Felice

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 28, 2026

PTP1B supports survival and regulates CFL1 and HSP90a abundance in trastuzumab-resistant HER2-positive breast cancer.

Vinay Mandati, Maria C. Panepinto, Christy Felice…·Nicholas K. Tonks

This study identifies PTP1B as a survival dependency in trastuzumab-resistant HER2-positive breast cancer, showing it regulates CFL1 and HSP90a abundance through dephosphorylation.

DOI 10.64898/2026.10.23.761095

humanexperimental assay

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ImmunologybioRxivPreprintJun 4, 2025

Crosslinked CXCR4 Signals Decreased Motility and Increased Adhesion of T Cells

Jordan A. Pearson, Jung‐In Yang, Sean Krivitsky…·Douglas T. Fearon

This study shows that crosslinked CXCR4 on T cells reduces their motility and increases adhesion through a non-Gi-dependent pathway involving PTK2B and integrin β4.

DOI 10.1101/2025.06.04.652236

humanproteomics

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