Author

Jung‐In Yang

Cold Spring Harbor LaboratoryORCID 0000-0003-0685-355XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Douglas T. FearoniD· 2 shared Z. Larkin KelleyiD· 2 shared David Arthur TuvesoniD· 1 shared Dexter W. Adams· 1 shared Francesca MinicozziiD· 1 shared Jonathan P. KastaniD· 1 shared Jordan A. PearsoniD· 1 shared Paolo CifaniiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersCell Biology

Douglas T. FearonORCID

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2 papers

Recent·Most cited

Cell BiologyProceedings of the National Academy of SciencesPeer-reviewedJul 1, 2025

Signal peptide-independent secretion of keratin-19 by pancreatic cancer cells

Philip Moresco, Jonathan P. Kastan, Jung‐In Yang…·Douglas T. Fearon

This study shows pancreatic cancer cells secrete keratin-19 (KRT19) without a signal peptide by entering the ER via its head domain and through secretory autophagy, enabling CXCL12 capture to exclude T cells.

8 citations

humanproteomics

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ImmunologybioRxivPreprintJun 4, 2025

Crosslinked CXCR4 Signals Decreased Motility and Increased Adhesion of T Cells

Jordan A. Pearson, Jung‐In Yang, Sean Krivitsky…·Douglas T. Fearon

This study shows that crosslinked CXCR4 on T cells reduces their motility and increases adhesion through a non-Gi-dependent pathway involving PTK2B and integrin β4.

DOI 10.1101/2025.06.04.652236

humanproteomics

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