NeurosciencebioRxivPreprint
Inhibition of histone lysine demethylase restores learning and memory in aged mice
Shail Ratna Bhatt, Lachlan Ford MacBean, Enikö A. Kramár…·M. Albert Basson
This study shows that inhibiting LSD1, a histone demethylase, restores learning and memory in aged mice by reversing age-related defects in H3K4me3 dynamics and synaptic plasticity.
DOI 10.64898/2025.12.22.695858