Author

Xin Yu

Baylor College of MedicineORCID 0009-0008-2722-0667Unclaimed ORCID profile · follow to get notified of new preprints

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Xin Yu9 papers · Baylor College of Medicine

Biology Disciplines

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Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:proteomics· 1

Frequent Co-Authors

Bin YangiD· 1 shared Changsheng SHAOiD· 1 shared Chao Liu· 1 shared Dong LuiD· 1 shared Feng Li· 1 shared Hanfeng LiniD· 1 shared Haotian Hu· 1 shared Jianhui BiniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPharmacology & Toxicology

Bin YangORCID

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2 papers

Recent·Most cited

Pharmacology & ToxicologyJournal of Medicinal ChemistryPeer-reviewedAug 11, 2026

Discovery and Development of First-in-Class Cereblon-Recruiting RIPK1 Degraders

Dong Lu, Xin Yu, Hanfeng Lin…·Jin Wang

This study develops LD5095, a novel cereblon-recruiting RIPK1 degrader, showing potent RIPK1 degradation and tumor sensitization to immune checkpoint inhibitors.

1 citation

experimental assaydrug response / drug discovery

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Cell BiologybioRxivPreprintMar 16, 2026

Nanosecond laser-driven proton FLASH spares normal tissue cells by sustaining mitochondrial homeostasis and attenuating ferroptosis

Changsheng SHAO, Yu Zhang, Pengzhi He…·Qing Huang

This study shows that nanosecond laser-driven proton FLASH-RT spares normal tissue by preserving mitochondrial homeostasis and reducing ferroptosis, while maintaining tumor-killing efficiency.

DOI 10.64898/2026.03.13.711531

humanproteomics

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