Quentinn Pearce

This study shows that mitochondrial cardiolipin deficiency disrupts electron transport chain function, leading to oxidative stress and promoting MASH in mice and humans.

The paper describes a reversible form of suspended animation in C. elegans induced by high population density and identifies molecular mechanisms regulating its induction and termination.

This study identifies lipid metabolic reprogramming as a conserved mechanism conferring hypoxic and aging resilience in Arctic ground squirrels and C. elegans.

This study shows that heme biosynthesis regulates BCAA catabolism and thermogenesis in brown adipose tissue by affecting UCP1 and mitochondrial function.