Bryan Granger

This study investigates CHAMP1 mutations' effects on neuronal development using patient-derived neurons, revealing disruptions in DNA repair, membrane excitability, and synaptic connectivity.

This study shows that oxidation of ΔFOSB at Cys172 regulates its DNA binding and gene expression in the hippocampus, affecting cognitive function under oxidative stress.

This study identifies leptin receptor-positive neurons in the insula that regulate feeding behavior and body weight through direct interoceptive input.

The paper builds a single-nucleus RNA-sequencing landscape of the SVZ in GBM patients and identifies therapeutic targets in the T_SVZ microenvironment.

This study shows that high-affinity CAR signaling in human Tregs leads to increased cytotoxicity and inflammatory cytokine production, while lower affinity reduces these effects.