Parastoo Amlashi

Development and application of nbLIBRA-seq for high-throughput discovery of antigen-specific nanobodies

This paper develops and validates nbLIBRA-seq, a method for high-throughput antigen-specific nanobody discovery in immunized alpacas, demonstrating its effectiveness in identifying nanobodies against CD71 and viral antigens.

Prefusion-specific glycoprotein B human antibodies protect against neonatal HSV-2 infection

The paper identifies prefusion-specific human antibodies against HSV-2 gB that neutralize both HSV-1 and HSV-2 and protect neonatal mice.

Contrastive Learning Enables Epitope Overlap Predictions for Targeted Antibody Discovery

This paper develops computational methods to predict epitope overlaps in antibodies, showing improved accuracy using contrastive learning and demonstrating their utility in antibody discovery.

Vaccines combining slow delivery and follicle targeting of antigens increase germinal center B cell clonal diversity and clonal expansion

This study shows that combining slow antigen delivery and follicle-targeting adjuvants enhances germinal center B cell diversity and clonal expansion in mice.