Author

Christalyn Ausler

Whitehead Institute for Biomedical ResearchORCID 0009-0008-9044-4380Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Organism:E. coli· 1 Approach:genetic perturbation / CRISPR· 1 Assay:proteomics· 1

Frequent Co-Authors

Ankur JainiD· 2 shared Amy DeikiD· 1 shared Bingbing YuaniD· 1 shared Heather R. KeysiD· 1 shared Ivan Susin PiresiD· 1 shared Jillian Stark· 1 shared Louisa Girard· 1 shared Luke S. FerroiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiophysics

Ankur JainORCID

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2 papers

Recent·Most cited

BiophysicsProceedings of the National Academy of SciencesPeer-reviewedSep 14, 2026

Maintaining transcriptome solubility constrains mRNA sequence composition

Marco Todisco, Christalyn Ausler, Ankur Jain

The paper shows that mRNA sequences have evolved to minimize self-association, maintaining transcriptome solubility through stable folding and reduced intermolecular contacts.

2 citations

E. colihuman

𝕏 PostBluesky

Cell BiologyCellPeer-reviewedAug 14, 2026

Polyamines buffer labile iron to suppress ferroptosis

Pushkal Sharma, Heather R. Keys, Ryan P. Mansell…·Ankur Jain

This study shows polyamines buffer labile iron to suppress ferroptosis by linking polyamine metabolism to iron homeostasis through a genome-wide CRISPR screen and fluorescent reporter.

12 citationstop 1%

humanproteomics

𝕏 PostBluesky