Noora Virtanen

This study identifies a non-canonical role for Jagged1 in regulating mechanosensitive kinase activity in endothelial cells under mechanical stress.

The paper identifies Myo1c as a factor interacting with Jag1 in endothelial cells, showing its role in Jag1 trafficking under shear stress.

This study uses phosphoproteomic analysis in zebrafish to show that ErbB inhibitors affect multiple signaling pathways, leading to similar physiological phenotypes.

This study shows Notch2 drives canonical Notch signaling in smooth muscle differentiation, while Notch3 requires higher doses to activate transcription due to weaker RBPJκ interaction, with implications for artery-specific diseases.

This study shows that zebrafish embryos are sensitive to heat stress and that certain compounds enhance their neurological and cardiac toxicity under heat stress.