Author

Franco Izzo

Cornell UniversityORCID 0000-0002-5813-6504Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ATAC-seq· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:ChIP-seq· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Dan Avi LandauiD· 4 shared Catherine J. PotenskiiD· 2 shared Eirini P. PapapetrouiD· 2 shared Ivan RaimondiiD· 2 shared Levan MekerishviliiD· 2 shared Saravanan GanesaniD· 2 shared Alyssa C. IndartiD· 1 shared Angelo D’AlessandroiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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4 shared papersGenomics

Dan Avi LandauORCID

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Author profile →

4 papers

Recent·Most cited

Single-cell mapping of regulatory DNA:Protein interactions

Wei-Yu Chi, Sang-Ho Yoon, Evrim Goksel, Levan Mekerishvili, Joe Pelt, Yiyun Lin, Tamara Prieto, John Zinno, Saravanan Ganesan, Catherine J. Potenski, Franco Izzo, Dan Avi Landau, Ivan Raimondi

This paper introduces D&D-seq, a single-cell method to map DNA:Protein interactions with high specificity and resolution, and applies it to study TF binding in human cells.

Cell · Jun 1, 2026Peer-reviewedGenomics

Ontogeny Dictates Oncogenic Potential, Lineage Hierarchy, and Therapy Response in Pediatric Leukemia

Ke Wang, Shayan Saniei, Nikita Poddar, Isabella G. Martinez, Clifford Chao, Subrina Autar, Persephone Fiore, Saul Carcamo, Meghana Sreenath, Jack H. Peplinski, Rhonda E. Ries, Anna Huo-Chang Mei, Noshin Azra Rahman, Levan Mekerishvili, Miguel Quijada‐Álamo, , Eric Chi Wai So

This study shows that the developmental stage of hematopoietic stem cells influences leukemic transformation, lineage hierarchy, and therapy response in pediatric leukemia.

Cancer Discovery · Dec 6, 2025Peer-reviewedCancer Biology

Single-cell genotype-phenotype mapping identifies therapeutic vulnerabilities in VEXAS syndrome

Saravanan Ganesan, Rebecca M. Murray, Jesús Alfonso López Sotélo, Elliot O. Eton, Kouhei Takashima, Theo Botella, Kai Beattie, Alyssa C. Indart, Nada Chraiki, Carolyne Croizier, Franco Izzo, Catherine J. Potenski, Samuele G. Marro, Zhijie Wu, Shouguo Gao, , Dan Avi Landau

This study uses single-cell multi-omics to map genotype-to-phenotype relationships in VEXAS syndrome, identifying PERK pathway activation as a therapeutic target.

bioRxiv · May 19, 2024 · PreprintGenomics

EpiMethylTag simultaneously detects ATAC-seq or ChIP-seq signals with DNA methylation

Priscillia Lhoumaud, Gunjan Sethia, Franco Izzo, Theodore Sakellaropoulos, Valentina Snetkova, Simon E. Vidal, Sana Badri, MacIntosh Cornwell, Dafne Campigli Di Giammartino, Kyu‐Tae Kim, Effie Apostolou, Matthias Stadtfeld, Dan Avi Landau, Jane A. Skok

EpiMethylTag combines ATAC-seq or ChIP-seq with bisulfite conversion to simultaneously assess chromatin accessibility/TF binding and DNA methylation.

Genome biology · Nov 21, 2019Peer-reviewedGenomics