Author

James Jaworski

Vanderbilt University Medical CenterORCID 0009-0009-2852-4088Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Assay:GWAS summary statistics· 2 Organism:human· 2 Approach:statistical model· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:GWAS / association mapping· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Todd L. EdwardsiD· 3 shared Digna R. Velez EdwardsiD· 2 shared Alan DaughertyiD· 1 shared Albert Phillip OwensiD· 1 shared Alexis T. Akerele· 1 shared Anthony R. SpuzzilloiD· 1 shared Atlas KhaniD· 1 shared Bahram NamjouiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersGenetic & Genomic Medicine

Todd L. EdwardsORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintAug 28, 2026

TRACE: A FINE-TUNED BIOMEDICAL LANGUAGE MODEL FOR DIRECTIONALLY INFORMED DRUG REPURPOSING FROM TRANSCRIPTOME-WIDE ASSOCIATION STUDIES

Christopher O. Otieno, Hannah M. Seagle, Alexis T. Akerele…·Todd L. Edwards

TRACE uses a fine-tuned biomedical language model to identify drug-gene pairs from TWAS data, achieving high recovery rates in validation studies.

DOI 10.64898/2026.08.25.26361263

humanGWAS summary statistics

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Genetic & Genomic MedicineNature CommunicationsPeer-reviewedAug 20, 2025

Multi-ancestry meta-analysis of keloids uncovers novel susceptibility loci in diverse populations

Catherine A. Greene, Gabrielle Hampton, James Jaworski…·Jacklyn N. Hellwege

This study identifies 21 novel genetic loci associated with keloids through a multi-ancestry GWAS, highlighting integrin signaling and fibrosis pathways.

15 citations

humanGWAS summary statistics

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PathologybioRxivPreprintOct 29, 2024

Platelets are Protective in Early Abdominal Aortic Aneurysm Formation

Hannah Russell, Anthony R. Spuzzillo, Tyler W. Benson…·Albert Phillip Owens

This study shows that platelet inhibition increases rupture risk in early abdominal aortic aneurysm models in mice.

2 citations

mouseexperimental assay

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