Albert Phillip Owens

Computational and Experimental Evaluation of a Flow-Conditioning Anastomotic Device for Arteriovenous Fistula Maturation

This study evaluates a flow-conditioning anastomotic device to improve AVF hemodynamics and reduce endothelial injury by normalizing wall shear stress.

Attenuation of Atherosclerosis with PAR4 Deficiency: Differential Platelet Outcomes in apoE-/- vs. Ldlr-/- Mice

This study shows that PAR4 deficiency reduces atherosclerosis in Ldlr-/- mice, with effects mediated by hematopoietic cells, particularly platelets, and highlights differences in platelet reactivity between apoE-/- and Ldlr-/- models.

Platelets are Protective in Early Abdominal Aortic Aneurysm Formation

This study shows that platelet inhibition increases rupture risk in early abdominal aortic aneurysm models in mice.

HuR inhibition reduces post-ischemic cardiac remodeling by dampening acute inflammatory gene expression and the innate immune response

This study shows that inhibiting HuR reduces cardiac remodeling after ischemia-reperfusion injury by dampening inflammatory gene expression and immune response, but not initial infarct size.