Author

Y. Chen

University of PennsylvaniaORCID 0009-0009-4678-3868Unclaimed ORCID profile · follow to get notified of new preprints

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Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1

Frequent Co-Authors

Hardik MakkariD· 2 shared Kyle H. ViningiD· 2 shared Nghi M. TraniD· 2 shared Amanda S. Bluem· 1 shared Fatemeh Tavakoli JoorabiiD· 1 shared Kang I. KoiD· 1 shared Kexin ZhangiD· 1 shared Rebecca G. WellsiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 28 mutual co-author links

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2 shared papersBioengineering

Hardik MakkarORCID

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2 papers

Recent·Most cited

BioengineeringbioRxivPreprintMay 23, 2026

Mechanical licensing of functional dendritic cell states for enhanced T cell priming

Yi Chen, Amanda S. Bluem, Fatemeh Tavakoli Joorabi…·Kyle H. Vining

This paper shows that mechanical stress relaxation in dendritic cells (DCs) influences their functional states, enhancing T cell priming through improved antigen presentation and migration.

DOI 10.64898/2026.05.19.725170

𝕏 PostBluesky

BioengineeringbioRxivPreprintOct 20, 2025

Matrix Stiffness Governs Fibroblast-Driven Immune Homeostasis in Gingival Tissues

Hardik Makkar, Nghi Tran, Y. Chen…·Kyle H. Vining

This study shows that matrix stiffness influences fibroblast-driven immune responses in gingival tissues, with stiff matrices reducing inflammation through non-canonical NFκB and epigenetic pathways.

1 citation

humanproteomics

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