Jungeui Hong

This study uses single-nucleus DNA sequencing to analyze pancreatic cancer evolution, revealing patterns of mutation and copy number variation across clinical scenarios.

The paper analyzes transcriptomic changes in metastatic pancreatic cancer using a patient's autopsy data to identify site-specific gene programs and clonal phylogeny.

The paper introduces TrUMIseq adapters with unique molecular identifiers to improve the accuracy of quantitative sequencing by better distinguishing PCR duplicates from true molecular duplicates.

This study shows that adaptive evolution of gene expression involves tuning TF binding affinities while maintaining gene regulatory network topology in yeast.