Author

Madiha Mohieldin Merghani

Universitätsmedizin GöttingenORCID 0009-0009-6114-2145Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Tiago F. OuteiroiD· 3 shared André FischeriD· 1 shared Anton Zhornyak· 1 shared Avika ChopraiD· 1 shared Bilyana PopovaiD· 1 shared Brit MollenhaueriD· 1 shared C. Alexander BoeckeriD· 1 shared Christiane Fahlbusch· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCell Biology

Tiago F. OuteiroORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cell BiologybioRxivPreprintJun 15, 2026

LRRK2/LRRK1 interactions modulate Rab7 activity and inhibit lysosomal exocytosis

Madiha Mohieldin Merghani, Ellen Gerhardt, Maiken Hesse…·Tiago F. Outeiro

This study investigates the interaction between LRRK1 and LRRK2, showing they modulate Rab7 activity and lysosomal exocytosis, with starvation reducing their interaction and impairing lysosomal homeostasis.

DOI 10.64898/2026.06.12.731951

humanexperimental assay

𝕏 PostBluesky

Cell BiologyAging CellPeer-reviewedMay 28, 2026

Blm10/PA200-activated 20S proteasomes promote α-synuclein degradation and bypass proteasome inhibition in Parkinson disease models

Tariq Tammam Ali, Anton Zhornyak, Madiha Mohieldin Merghani…·Gerhard H. Braus

This study shows that Blm10/PA200 activates 20S proteasomes to degrade α-synuclein and resist inhibition, improving proteostasis in Parkinson's disease models.

2 citationstop 3%

yeastmouse

𝕏 PostBluesky

NeurosciencebioRxivPreprintSep 12, 2024

The epitranscriptomic m6A RNA modification modulates synaptic function in ageing and in a mouse model of synucleinopathy

Avika Chopra, Mary Xylaki, Fanzheng Yin…·Tiago F. Outeiro

This study investigates the role of m6A RNA modification in synaptic function and ageing using a mouse model of synucleinopathy, finding age-related changes in m6A methylation of synaptic genes.

2 citations

mousebulk RNA-seq

𝕏 PostBluesky