Author
Vanderbilt UniversityORCID 0009-0009-6450-9475Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Mirazul Islam, Matthew E. Bechard, Yilin Yang…·Robert J. Coffey
The paper uses clonal analysis to reveal species-specific differences in intestinal regeneration and stem cell dynamics in mice and humans.
Paige N Spencer, Jiawei Wang, Erin P. Smith…·Ken S. Lau
The paper identifies a pathobiont-epithelial IDO1 pathway that drives region-specific susceptibility to inflammatory bowel disease in the ascending colon.
Mirazul Islam, Yilin Yang, Alan J. Simmons…·Ken S. Lau
The paper introduces NSC-seq, a CRISPR-based molecular clock to track temporal and clonal events in development and precancer, revealing polyancestral initiation in colonic precancers.
Jia Li, Alan J. Simmons, Caroline V. Hawkins…·Qi Liu
The paper identifies a novel epithelial cell type, LND, in Crohn's disease that is associated with immune dysregulation and disease activity.
Cody N. Heiser, Alan J. Simmons, Frank L. Revetta…·Ken S. Lau
This study maps tumor evolution and microenvironment dynamics in colorectal cancer using spatial multi-omic data, identifying key genes associated with immune exclusion and prognosis.