Qi Liu

This study identifies ACTN4 as a non-muscle α-actinin in cardiac sarcomeres, showing it regulates contractility, hypertrophy, and heart remodeling without disease hallmarks.

The paper shows that Myt3 translation is deregulated in β-cells under obesity-induced stress, leading to β-cell dysfunction and glucose intolerance.

The paper examines molecular and cellular changes in thymic stromal and hematopoietic cells during the perinatal to juvenile transition in mice and humans, identifying key pathways and signaling changes.

This study shows Atf4 protects beta-cell function under high glucose but worsens beta-cell failure when combined with free fatty acids.

The paper identifies a novel epithelial cell type, LND, in Crohn's disease that is associated with immune dysregulation and disease activity.

This study identifies miR-100 and miR-125b as regulators of 3D growth and invasiveness in cancer cells, showing they can be transferred extracellularly to silence target genes in recipient cells.

This study shows SCLC cells exist in a continuum of plastic states rather than discrete subtypes, with gene expression patterns linked to cancer hallmarks and potential therapeutic targets.

SpaGene finds spatial expression patterns without assuming a model, reportedly with more power and better scaling than existing methods, and extends to ligand-receptor colocalization.

The paper identifies four SCLC subtypes using a systems approach, with NEv2 being a new subtype, and finds master regulators and destabilizers using BooleaBayes.