PIEZOs regulate oligodendrocyte sheath formation, expansion, and myelination potential
Adam M. Coombs, Dongeun Heo, Daniel J. Orlin, Cody L. Call, Marie E. Bechler, Swetha E. Murthy, Ben Emery, Kelly R. Monk
This study shows that PIEZO1 and PIEZO2 channels in oligodendrocytes regulate sheath formation, expansion, and myelination by detecting mechanical cues.
bioRxiv · Apr 25, 2026 · PreprintNeuroscience