William Mau

Hippocampus and amygdala fear memory engrams re-emerge after contextual fear relapse

Ensemble remodeling supports memory-updating

This study identifies a mechanism where hippocampal ensembles are remodeled to support memory-updating in mice during spatial reversal tasks.

Minian: An open-source miniscope analysis pipeline

Minian is an open-source pipeline for analyzing single-photon in vivo calcium imaging data, offering low memory usage, interactive visualizations, and parameter exploration tools.

Consistent population activity on the scale of minutes in the mouse hippocampus

This study shows that hippocampal neurons in mice exhibit consistent firing sequences across seconds and minutes during experimental sessions.

Hippocampal spatial memory representations in mice are heterogeneously stable

The paper shows that hippocampal neurons in mice reorganize their activity patterns over time during a spatial memory task, with different cell populations changing at different rates.

Persistent trajectory-modulated hippocampal neurons support memory-guided navigation

The paper investigates trajectory-dependent splitter neurons in mice, finding they are more stable than place cells and support memory-guided navigation.

Retrosplenial cortical representations of space and future goal locations develop with learning

This study shows that RSC in rats develops spatial and future goal representations during learning, which correlate with navigation accuracy and are disrupted by lesions.