Christopher W. Wilson

This study shows ANGPTL7 affects immune cells in the optic nerve head, contributing to neurodegeneration in glaucoma, despite no effect on intraocular pressure.

This study compares proteomic profiles of aqueous humor and plasma between glaucoma and non-glaucomatous patients, identifying differentially abundant proteins linked to vascular integrity, inflammation, and neurodegeneration.

This study shows dsRNA triggers RIG-I signaling, leading to inflammation and RPE degeneration in AMD, with implications for pathogenesis.

This study uses bulk RNA sequencing on postmortem human eye tissue to identify gene and pathway changes associated with progression from intermediate to late-stage AMD, highlighting potential therapeutic targets.

This paper introduces a multiparametric grading system to stratify post-mortem glaucoma tissue by disease severity using structural and molecular markers.

This study investigates how APOE variants affect lipid trafficking in RPE cells, finding that APOE knockout and APOE2-expressing cells show lipid transport deficits, while APOE4-expressing cells upregulate APOE in response to lipid challenges.

This study investigates the role of Rasip1 in endothelial cell behaviors during angiogenesis and anastomosis in zebrafish, revealing its critical function in cell pairing and junction stability.