Author

Minkyoung Lee

University of BaselORCID 0000-0002-3956-7288Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 3 Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:differential expression· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:spatial domain detection· 2 Organism:zebrafish· 2

Frequent Co-Authors

Heinz‐Georg BeltingiD· 3 shared Markus AffolteriD· 3 shared Andreas E. MooriD· 2 shared Ilkka PaateroiD· 2 shared Jianmin YiniD· 2 shared Niels Schellinx· 2 shared Adam N. CarteiD· 1 shared Alejandro SifrimiD· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersDevelopmental Biology

Heinz‐Georg BeltingORCID

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5 papers

Recent·Most cited

SubCellSpace: Automated characterization of subcellular mRNA localization patterns in spatial transcriptomics

D. J. Wouters, Jose Ignacio Alvira Larizgoitia, Nynke Tilkema, Paulien Van Minsel, Ceyhun Alar, Nick Seeuws, Ilias Theodorus Koulalis, Minkyoung Lee, Niels Vandermeulen, Srivathsan Adivarahan, Sandrine Da Cruz, Katy Vandereyken, Andreas E. Moor, Bernard Thienpont, Thierry Voet, Alejandro Sifrim

SubCellSpace identifies and characterizes subcellular mRNA localization patterns in spatial transcriptomics data using a computational framework.

bioRxiv · Apr 30, 2026 · PreprintBioinformatics

Initiation of Lumen Formation from Junctions via Differential Actomyosin Contractility Regulated by Dynamic Recruitment of Rasip1

Jianmin Yin, Niels Schellinx, Ludovico Maggi, Kathrin Gundel, Cora Wiesner, Maria Paraskevi Kotini, Minkyoung Lee, Li‐Kun Phng, Heinz‐Georg Belting, Markus Affolter

This study identifies Rasip1's role in regulating actomyosin contractility to initiate lumen formation from junctions in zebrafish.

Nature Communications · Nov 9, 2024Peer-reviewedDevelopmental Biology

A massively parallel reporter assay reveals focused and broadly encoded RNA localization signals in neurons

Martin Mikl, Davide Eletto, Malak Nijim, Minkyoung Lee, Atefeh Lafzi, Farah Mhamedi, Orit David, Simona Baghai Sain, Kristina Handler, Andreas E. Moor

The paper uses a massively parallel reporter assay to identify RNA localization signals in neurons, revealing focused and broadly encoded motifs that influence mRNA localization to neurites and soma.

Nucleic Acids Research · Sep 8, 2022Peer-reviewedGenomics

Control of dynamic cell behaviors during angiogenesis and anastomosis by Rasip 1

Minkyoung Lee, Charles Betz, Jianmin Yin, Ilkka Paatero, Niels Schellinx, Adam N. Carte, Christopher W. Wilson, Weilan Ye, Markus Affolter, Heinz‐Georg Belting

This study investigates the role of Rasip1 in endothelial cell behaviors during angiogenesis and anastomosis in zebrafish, revealing its critical function in cell pairing and junction stability.

Development · Jun 21, 2021Peer-reviewedDevelopmental Biology

Junction-based lamellipodia drive endothelial cell rearrangements in vivo via a VE-cadherin/F-actin based oscillatory ratchet mechanism

Ilkka Paatero, Loïc Sauteur, Minkyoung Lee, Anne K. Lagendijk, Daniel Heutschi, Dimitri Bieli, Benjamin M. Hogan, Markus Affolter, Heinz‐Georg Belting

The paper identifies junction-based lamellipodia (JBL) as structures driving endothelial cell movement during vascular remodeling, showing their dependence on F-actin and VE-cadherin.

bioRxiv · Nov 1, 2017 · PreprintDevelopmental Biology