Subacute Inhalation of Ultrafine Particulate Matter Triggers Inflammation Without Altering Amyloid Beta Load in 5xFAD mice.

Liudmila Saveleva; Petra Vartiainen; Veronika Górová; Sweelin Chew; Irina Belaya; Henna Konttinen; Martina Zucchelli; Paula Korhonen; Emma Kaartinen; Miika Kortelainen; Heikki Lamberg; Olli Sippula; Tarja Malm; Pasi Jalava; Katja M. Kanninen

doi:10.1016/j.neuro.2022.01.001

NeuroscienceNeuroToxicologyJan 6, 2022

Peer-reviewed journal article

Subacute Inhalation of Ultrafine Particulate Matter Triggers Inflammation Without Altering Amyloid Beta Load in 5xFAD mice.

Liudmila Saveleva iD, Petra Vartiainen, Veronika Górová, Sweelin Chew iD, Irina Belaya iD, Henna Konttinen, Martina Zucchelli, Paula Korhonen iD, Emma Kaartinen iD, Miika Kortelainen iD, Heikki Lamberg iD, Olli Sippula iD, Tarja Malm iD, Pasi Jalava iD, Katja M. Kanninen iD

Abstract

Epidemiological studies reveal that air pollution exposure may exacerbate neurodegeneration. Ultrafine particles (UFPs) are pollutants that remain unregulated in ambient air by environmental agencies. Due to their small size ( View larger version (27K): org.highwire.dtl.DTLVardef@479511org.highwire.dtl.DTLVardef@18bc59aorg.highwire.dtl.DTLVardef@15a0240org.highwire.dtl.DTLVardef@49f911_HPS_FORMAT_FIGEXP M_FIG C_FIG

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