Author

Henna Konttinen

University of Eastern Finland

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Paula KorhoneniD· 3 shared Tarja MalmiD· 3 shared Alice PébayiD· 2 shared Anastasia ShakirzyanovaiD· 2 shared Damián HernándeziD· 2 shared Irina BelayaiD· 2 shared Jari KoıstınahoiD· 2 shared Katja M. KannineniD· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Paula KorhonenORCID

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3 papers

Recent·Most cited

Microglial amyloid beta clearance is driven by PIEZO1 channels

Henna Konttinen, Valeria Sitnikova, Yevheniia Ishchenko, Anastasia Shakirzyanova, Luca Giudice, Irene F. Ugidos, Mireia Gómez‐Budia, Nea Korvenlaita, Sohvi Ohtonen, Irina Belaya, Mohammad Feroze Fazaludeen, Nikita Mikhailov, Maria Gotkiewicz, Kirsi Ketola, Šárka Lehtonen, , Tarja Malm

This study shows that activating PIEZO1 channels in microglia improves amyloid beta clearance in AD models by enhancing survival, phagocytosis, and lysosomal activity.

bioRxiv · Mar 18, 2022 · PreprintNeuroscience

Subacute Inhalation of Ultrafine Particulate Matter Triggers Inflammation Without Altering Amyloid Beta Load in 5xFAD mice.

Liudmila Saveleva, Petra Vartiainen, Veronika Górová, Sweelin Chew, Irina Belaya, Henna Konttinen, Martina Zucchelli, Paula Korhonen, Emma Kaartinen, Miika Kortelainen, Heikki Lamberg, Olli Sippula, Tarja Malm, Pasi Jalava, Katja M. Kanninen

NeuroToxicology · Jan 6, 2022Peer-reviewedNeuroscience

Microglia orchestrate neuronal activity in brain organoids

Ilkka Fagerlund, Antonios Dougalis, Anastasia Shakirzyanova, Mireia Gómez‐Budia, Henna Konttinen, Sohvi Ohtonen, Mohammad Feroze Fazaludeen, Marja Koskuvi, Johanna Kuusisto, Damián Hernández, Alice Pébay, Jari Koıstınaho, Šárka Lehtonen, Paula Korhonen, Tarja Malm

This study shows that incorporating microglial progenitors into human brain organoids supports neuronal maturation and synaptic activity.

bioRxiv · Dec 8, 2020 · PreprintNeuroscience