Topic · Psychiatry and Mental health · Medicine

Dementia and Cognitive Impairment Research

OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.

2 papers

Synapse protein signatures in cerebrospinal fluid and plasma predict cognitive maintenance versus decline in Alzheimers disease

Hamilton Se‐Hwee Oh, Deniz Yagmur Urey, Linda Karlsson, Zeyu Zhu, Yuanyuan Shen, Amelia Farinas, Jigyasha Timsina, Michael R. Duggan, Jingsha Chen, Ian Hunter Guldner, Nader Morshed, Chengran Yang, Daniel Western, Muhammad Ali, Yann Le Guen, , Tony Wyss‐Coray

CSF YWHAG:NPTX2 synapse protein ratio, from proteomics of 3,416 individuals across six cohorts, explains cognitive impairment beyond amyloid and tau and predicts decline (hazard ratio 15.4).

Nature Medicine · Mar 31, 2025Peer-reviewedNeuroscience✦ In-depth digest

DeepAD: Alzheimer’s Disease Classification via Deep Convolutional Neural Networks using MRI and fMRI

Saman Sarraf, Danielle D. DeSouza, John A. E. Anderson, Ghassem Tofighi, Alzheimer’s Disease Neuroimaging Initiative

Caffe LeNet and GoogleNet trained on 2D slices from ADNI scans of adults over 75 report 98.84% to near-perfect accuracy, and 100% per subject for MRI after majority voting.

bioRxiv · Jan 14, 2017 · PreprintBioinformatics✦ In-depth digest