Muhammad Ali

The paper introduces SkeletAge, a bulk RNA-seq-based aging clock that identifies 26 novel genes in skeletal muscle aging and links them to aging phenotypes and drug targets.

CSF YWHAG:NPTX2 synapse protein ratio, from proteomics of 3,416 individuals across six cohorts, explains cognitive impairment beyond amyloid and tau and predicts decline (hazard ratio 15.4).

iSODA is a web-based tool for analyzing single- and multi-omics data, offering visualization, normalization, and integration methods like MOFA and SNF.

This study identifies four novel genetic loci associated with soluble TREM2 levels in CSF through GWAS and provides functional validation of their roles in Alzheimer's disease.

The paper harmonizes CSF and amyloid imaging biomarkers using a Z-score approach and compares it to existing methods in GWAS analyses.

This study investigates the association between Klotho heterozygosity and Alzheimer's disease risk in APOE4 carriers using multiple AD endophenotypes from large cohorts.