Author
Washington University in St. LouisORCID 0000-0003-4577-5590Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
7 papers
Recent·Most cited
Hamilton Se‐Hwee Oh, Deniz Yagmur Urey, Linda Karlsson…·Tony Wyss‐Coray
CSF YWHAG:NPTX2 synapse protein ratio, from proteomics of 3,416 individuals across six cohorts, explains cognitive impairment beyond amyloid and tau and predicts decline (hazard ratio 15.4).
Federica Anastasi, Patricia Genius, Blanca Rodríguez‐Fernández…·Natàlia Vilor‐Tejedor
The paper identifies TIMP2 as a blood protein associated with improved cognitive performance in humans using polygenic scores derived from protein quantitative trait loci data.
Lihua Wang, Niko-Petteri Nykänen, Daniel Western…·Carlos Cruchaga
This study identifies four novel genetic loci associated with soluble TREM2 levels in CSF through GWAS and provides functional validation of their roles in Alzheimer's disease.
Laura Ibáñez, Jorge Alberto Bahena, Chengran Yang…·Bruno A. Benítez
The paper uses GWAS, PRS, and MR to show a genetic link between Parkinson's disease and CSF Aβ42 and APOE locus.
Chengran Yang, Fabiana Geraldo Farias, Laura Ibáñez…·Carlos Cruchaga
The paper integrates genomic and proteomic data across multiple tissues to identify protein quantitative loci (pQTL) and their implications for neurodegenerative diseases.
Zeran Li, Fabiana Geraldo Farias, Umber Dube…·Carlos Cruchaga
The paper identifies a genetic variant in TMEM106B associated with increased neuronal proportion in neurodegenerative and cognitive normal cohorts, suggesting a role in neuronal protection.