Blood Pressure and Hypertension Studies

Enhancing the Clinical Utility of Renal Denervation Through Efficient Physiologic Monitoring

This study evaluates whether shorter data segments can reliably assess sympathetic vasomotion for renal denervation, finding that four-minute recordings are sufficient for group-level decisions while ten-minute recordings offer greater individual precision.

Limitations of renal arterial hemodynamic measures as candidate biomarkers of renal sympathetic innervation

This study evaluates whether renal arterial hemodynamic measures reflect renal sympathetic innervation in preclinical models, finding inconsistent results.

Associations Between the IL-23/IL-17A Cytokine Axis and Ambulatory Blood Pressure in Older Adults

This study investigates the association between the IL-23/IL-17A cytokine axis and ambulatory blood pressure in older adults, finding positive correlations between IL-23 and diastolic BP and links between IL-17A and systolic BP.

Sex-specific dichotomy of chronic mild stress effects on blood pressure and longitudinal measurements of renal sympathetic nerve activity: are females really protected?

This study investigates the effects of chronic mild stress on blood pressure and renal sympathetic nerve activity in male and female rats, showing that renal denervation reduces BP in males but not females, and that females exhibit increased renal sympathetic nerve activity despite normal BP.

A Multi-Omics Approach to Defining Target Organ Injury in Youth with Primary Hypertension

This study identifies VASH1 and HYAL1 as potential mediators of cardiovascular target organ injury in youth with high blood pressure using multi-omics profiling.

Novel and Known Genetic Players in Hypertension: From Gene Expression to Striking Insights

This study identifies novel and known genetic contributors to hypertension using RNA-seq and eQTL analyses, highlighting potential drug targets and pathways.

Sympathetic Vasomotion Reflects Catheter-based Radiofrequency Renal Denervation

This study shows that renal sympathetic vasomotion decreases after catheter-based radiofrequency renal denervation, indicating its potential as a feedback tool for the procedure.

Predicted Effect of Circadian Regulation of Renal Transporters in a Hypertensive Rat

The paper simulates the diurnal effects of diuretics on renal transporters in normotensive and hypertensive kidneys, showing time-of-day differences in natriuresis, diuresis, and kaliuresis.

Proteomic Alterations Associated with Oral Contraceptive Use in Hypertensive Premenopausal African American Women

The paper identifies proteomic signatures linked to oral contraceptive use in hypertensive premenopausal African American women, revealing associations with neurohormonal, immune, and lipid pathways.

Low-dose colchicine treatment improves vasorelaxation, reduces arterial remodeling and attenuates blood pressure increases in spontaneously hypertensive rats

Exenatide administration time determines the effects on blood pressure dipping in db/db mice via modulation of food intake and sympathetic activity

This study shows that exenatide administration time affects blood pressure dipping in db/db mice by altering food intake and sympathetic activity, with efficacy dependent on food availability and circadian timing.

Physical activity reduces the effect of adiposity genetic liability on hypertension risk in the UK Biobank cohort

The paper examines how physical activity interacts with genetic liability for adiposity to influence hypertension risk in UK Biobank participants, finding a protective effect in European ancestry individuals.

Influence of blood pressure on pneumonia risk: Epidemiological association and Mendelian randomisation in the UK Biobank

This study finds that elevated blood pressure increases pneumonia risk and reduces pulmonary function, supported by both epidemiological and Mendelian randomisation analyses in the UK Biobank.

Multilevel modelling, prevalence and predictors of hypertension in Ghana: Evidence from Wave 2 of the World Health Organizations Study on Global AGEing and adult health.

This study uses multilevel regression to identify risk factors for hypertension in Ghana, finding age, obesity, marital status, health state, and self-care difficulty as significant predictors.

Association of Peripheral Blood Pressure with Grey Matter Volume in 19- to 40-Year-Old Adults

This study investigates the relationship between blood pressure and grey matter volume in young adults, finding that higher blood pressure correlates with reduced grey matter volume in specific brain regions.