Topic · Immunology · Immunology and Microbiology
OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.
124 papers
Margaret J. Lange, Donald H. Burke, John Charles Chaput
The paper evaluates a threose nucleic acid (TNA) oligonucleotide derived from a CpG sequence and finds it induces immune responses in B cell lines with minimal effects on proliferation.
Nucleic Acid Therapeutics · Dec 11, 2018Peer-reviewedSynthetic Biology
Ailís O’Carroll, Brieuc Chauvin, James Brown, Ava Meagher, Joanne Coyle, Dominic J. B. Hunter, Akshay Bhumkhar, Thomas Ve, Boštjan Kobe, Emma Sierecki, Yann Gambin
This study investigates how pathological mutations affect the prion-like polymerization of MyD88, showing that these mutations block polymerization and alter oligomer stability.
bioRxiv · Jun 20, 2018 · PreprintMolecular Biology
Elena Dimitrova, Leslie Ann Caromile, Reinhard Laubenbacher, Linda H. Shapiro
The paper constructs a multiscale model of TLR4 signaling in ischemic injury to predict therapeutic outcomes and identify safe targets.
BMC Systems Biology · Apr 10, 2018Peer-reviewedSystems Biology