Topic · Cell Biology · Biochemistry, Genetics and Molecular Biology
OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.
394 papers
Patrick J. Rock, Austin G. Meyer, Chantell S. Evans…·Roger Bryan Sutton
The paper models how AD3 mutations in synaptotagmin 1's C2 domains affect Ca2+ binding pocket dynamics and explains their lethal effects through increased loop mobility and volume changes.
Nobutake Hosoi, Koji Shibasaki, Mayu Hosono…·Tetsushi Sadakata
This study shows that deletion of class II ARF causes essential tremors by impairing Nav1.6 trafficking to Purkinje cell axon initial segments.
Zack Zurawski, Analisa D. Thompson Gray, Lillian J. Brady…·Heidi E. Hamm
This study shows that disrupting Gβγ-SNARE interaction in mice leads to impaired gait, nociception, and hippocampal function, highlighting its role in GPCR-mediated presynaptic inhibition.
Sven Truckenbrodt, Abhiyan Viplav, Sebastian Jähne…·Silvio O. Rizzoli
The paper shows that aged synaptic vesicles are inactivated by SNAP25 contamination, which inhibits exocytosis and promotes co-localization with recycling endosomes.