Electrospun Nanofibers in Biomedical Applications

Highlighting strain rate dependent vibrational behavior of electrospun bundles for tendon/ligament and enthesis fascicle tissue regeneration

This study investigates how scaffold geometry and material affect vibrational behavior under mechanical stimulation in electrospun bundles for tendon/ligament and enthesis tissue regeneration.

RELATIONSHIP BETWEEN ACTUAL STRESS AND IN SITU MORPHOLOGICAL CHANGES IN THE MECHANICAL BEHAVIOR OF BIOMIMETIC POROUS HIERARCHICAL SCAFFOLDS

This paper examines how the mechanical behavior of biomimetic porous scaffolds changes with strain by analyzing evolving morphology and stress-strain relationships.

Modular Noncovalent Functionalization of Electrospun Piezoelectric Scaffolds with Bioactive Nanocarriers

This paper develops a noncovalent method to functionalize piezoelectric scaffolds with bioactive nanocarriers, enabling sustained cytokine signaling for tissue and immune engineering.

Co-Electrospinning Extracellular Matrix with Polycaprolactone Enables a Modular Approach to Balance Bioactivity and Mechanics of a Multifunctional Bone Wrap

This study compares co-electrospinning and blend electrospinning of polycaprolactone and SIS for bone wrap fabrication, showing co-spun wraps improve handling, infection control, and angiogenesis.

Revealing the Auxetic Behavior of Biomimetic Multi-material and Region-specific Nanofibrous Scaffolds via Synchrotron Multiscale Digital Volume Correlation: Innovative Building Blocks for the Enthesis Regeneration

This study develops biomimetic nanofibrous scaffolds with auxetic properties for enthesis regeneration, showing their mechanical behavior matches natural tendon fascicles.

Hyaluronic Acid-Coated Melt Electrowritten Scaffolds Promote Myoblast Attachment, Alignment, and Differentiation

This paper develops HA-coated MEW scaffolds that enhance myoblast attachment, alignment, and differentiation compared to non-coated scaffolds.

Rational Design and Modeling of Auxetic Fiber Scaffolds for Soft Tissue Engineering via Melt Electrowriting

This study presents a computational framework for designing auxetic fiber scaffolds using Melt Electro-writing, validated through FEM modeling and experimental testing to achieve tailored mechanical properties for soft tissue engineering.

Enhanced Piezoelectric Performance of PVDF-TrFE Nanofibers through Annealing for Tissue Engineering Applications

This study enhances the piezoelectric properties of PVDF-TrFE nanofibers through annealing, showing improved mechanical and biological responses for tissue engineering.

Engineered collagen-coated scaffolds for tendon regeneration: a multifunctional drug delivery approach

This paper develops collagen-coated scaffolds for tendon regeneration, demonstrating effective drug delivery and cellular infiltration.

Mandrel Diameter is a Dominating Parameter for Fiber Alignment Control in Rotating Mandrel Electrospinning Systems

This study investigates the impact of mandrel diameter on fiber alignment, fraction, and diameter in electrospinning, finding it to be more influential than rotational speed.

A stretchable and biomimetic polyurethane membrane for lung alveolar in vitro modelling

This paper develops a biomimetic polyurethane membrane that mimics lung alveolar tissue mechanics and supports long-term cell culture.

Stable, Easy-to-Handle, Fully Autologous Electrospun Polymer-Peptide Skin Equivalent for Severe Burn Injuries

This paper develops a bioengineered skin equivalent using electrospun PCL functionalized with a bioactive peptide to treat severe burn injuries, showing improved wound closure and skin regeneration in mice.

Advanced Manufacturing of Coil-Reinforced Multilayer Vascular Grafts to Optimize Biomechanical Performance

The paper develops a multilayer vascular graft with a polymeric coil to improve kink resistance while maintaining compliance, using advanced manufacturing and finite element modeling to optimize biomechanical performance.

Amyloid peptide - synthetic polymer blends with enhanced mechanical and biological properties

This study blends amyloid peptides with poly(ethylene oxide) to create composite mats with enhanced mechanical and biological properties.

Rotary jet-spun porous microfibers as scaffolds for stem cells delivery to central nervous system injury

This study develops a PLA scaffold to enhance stem cell delivery and retention in a mouse stroke model, reducing lesion area and improving cell survival.