Allergic Rhinitis and Sensitization

Quantitative Model of the Ocular Immune Response during Seasonal Allergic Conjunctivitis

The paper develops a mathematical model of the ocular immune response in seasonal allergic conjunctivitis, showing it captures key features of disease progression and identifies potential therapeutic targets.

Estimating Daily Taxon-specific Tree Pollen at a 1-km Resolution in Atlanta, GA from 2020 to 2024

This study predicts daily taxon-specific tree pollen exposure at 1-km resolution in Atlanta from 2020 to 2024 using a machine learning model integrating dispersion, phenology, and monitoring data.

Development and translational validation of a novel mouse model for allergic rhinitis

This paper develops a novel mouse model of cat allergic rhinitis that recapitulates key clinical features and enables mechanistic and therapeutic studies.

Five years of national airborne pollen monitoring in South Africa: Biome-specific calendars to inform allergy diagnosis and prevention

This study presents five-year airborne pollen data from South Africa's biomes, identifying seasonal patterns and key pollen types to support allergy management.

Structure-guided deimmunisation of Fel d 1 suppresses allergic effector functions ex vivo

This study designs hypoallergenic variants of Fel d 1 by disrupting IgE-binding sites, showing reduced IgE reactivity and suppressed basophil activation ex vivo.

Anti-allergic Effect of Soluble Beta-glucan on Japanese Cedar Pollinosis and Mechanism Underlying Its Allergy-ameliorating Action

This study shows that soluble beta-glucan (SBG) reduces IgE production and sneezing in a sugi pollinosis mouse model by modulating immune responses and gut microbiota.

Sensitive colorimetric ELISA measuring salivary SBP-specific secretory IgA, its application to pollinosis SLIT

This paper develops a sensitive colorimetric ELISA to measure salivary SBP-specific secretory IgA levels in patients undergoing sublingual immunotherapy for pollinosis and finds increased SIgA levels after treatment.

Fungal spore seasons advanced across the US over two decades of climate change

This study shows that fungal spore seasons advanced by 11-22 days across the US over two decades, but annual spore concentrations decreased, linked to climate variables.

Effect of Shufeng Xingbi Therapy on Th1/Th2 immune balance and intestinal flora in rats with allergic rhinitis

This study evaluates the effect of Shufeng Xingbi Therapy on Th1/Th2 immune balance and intestinal flora in allergic rhinitis rats, finding improvements in inflammation and immune markers.

Ovalbumin-loaded mesoporous silica nanoparticles for allergen specific immunotherapy

This study evaluates mesoporous silica nanoparticles loaded with ovalbumin as a safer and more effective allergen-specific immunotherapy, showing protection against anaphylaxis and a Th1/Treg immune profile in mice.

Predicting Blomia tropicalis allergens using a multiomics approach

This paper uses a multiomics approach to identify and predict allergens in Blomia tropicalis, revealing novel allergens and showing gene expression does not strictly correlate with protein abundance.

Crystal Structure of the Dog Allergen Can f 6

The paper presents the crystal structure of the dog allergen Can f 6 and compares its biophysical and biological properties to other lipocalins.

Analysis of Maize Profilin-4 Isoform as an allergen

The paper analyzes the allergenic potential of maize profilin-4 isoform by examining its physicochemical properties and predicting B cell epitopes using immune-informatics tools.