Joaquín Sanz

Development and translational validation of a novel mouse model for allergic rhinitis

This paper develops a novel mouse model of cat allergic rhinitis that recapitulates key clinical features and enables mechanistic and therapeutic studies.

Epigenetic impairment and blunted transcriptional response to Mycobacterium tuberculosis of alveolar macrophages from persons living with HIV

The paper investigates how HIV and antiretroviral therapy affect the transcriptional and epigenetic response of alveolar macrophages to Mycobacterium tuberculosis.

Social history and exposure to pathogen signals modulate social status effects on gene regulation in rhesus macaques

This study shows that social status affects gene expression in immune cells of rhesus macaques, with effects modulated by pathogen exposure, type, and social history.

Social status alters chromatin accessibility and the gene regulatory response to glucocorticoid stimulation in rhesus macaques

This study shows that social status affects chromatin accessibility and gene regulation in response to glucocorticoids in rhesus macaques, with stable effects on chromatin accessibility and reduced gene expression effects after treatment.