Hernia repair and management

Genetic Susceptibility to Incisional Hernia: Evaluation of Hernia Polygenic Risk Scores

This study evaluates polygenic risk scores for hernia susceptibility and finds they are associated with incisional hernia but do not improve clinical risk prediction beyond traditional factors.

Decoding the genetic architecture of hernia through genome-wide association and multi-trait analyses

This study identifies 243 genome-wide significant loci for hernia subtypes, reveals shared and distinct genetic factors, and identifies potential therapeutic targets.

Comprehensive genome-wide association study of different forms of hernia identifies more than 80 associated loci

This study identifies 81 genetic loci associated with different hernia types using genome-wide association analysis in the UK Biobank.

Selective Germline Genome Edited Pig Meninges Grafts for the Abdominal Wall Closure in Damage Control Surgery

This study explores the feasibility of using selective germline genome-edited pig meninges grafts for abdominal wall closure in damage control surgery, showing successful integration and revascularization in a rabbit model.