Topic · Oncology · Medicine
OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.
3 papers
Zhangfan Ding, 张家源, Hanyu Liu, Abhishek Chandra, Makarand V. Risbud, Anjali P. Kusumbe, Junyu Chen
This paper describes a standardized protocol for creating mouse models of bisphosphonate-related and radiation-induced jaw osteonecrosis using minimally invasive surgical and irradiation techniques.
STAR Protocols · Oct 5, 2026Peer-reviewedPathology
Yixin Shi, Haiyang Sun, Zijian Guo, Xian Liu, Xibo Pei, Jian Wang, Fanyuan Yu, Xingchen Peng, Quan Yuan, Anjali P. Kusumbe, Junyu Chen
This study identifies vascular and lymphatic dysfunction in BRONJ, revealing the COL2A1-CD44/SDC4 axis as a therapeutic target through multimodal analysis of mouse and human samples.
Nature Communications · Sep 10, 2026Peer-reviewedCell Biology
Lauren E. Surface, Damon T. Burrow, Jinmei Li, Jiwoong Park, Sandeep Kumar, Cheng Lyu, Niki Song, Zhou Yu, Abbhirami Rajagopal, Yangjin Bae, Brendan Lee, Steven R. Mumm, C. Charles Gu, Jonathan C. Baker, Mahshid Mohseni, , Timothy R. Peterson
The paper identifies ATRAID as a gene critical for the response to nitrogen-containing bisphosphonates, showing its role in drug efficacy and resistance in osteoporosis.
Science Translational Medicine · May 20, 2020Peer-reviewedGenomics