Mycobacterium research and diagnosis

Genetic Diversity of Non-Tuberculous Mycobacteria among Symptomatic TB negative Patients in Kenya

The paper identifies 43 NTM species in symptomatic TB-negative patients in Kenya, finding high diversity with M. avium complex as dominant and significant regional and age associations.

The Role of Biofilms, Bacterial Phenotypes, and Innate Immune Response in Mycobacterium avium Colonization to Infection

This paper develops a 3D agent-based model to simulate early MAC infection dynamics, showing how biofilms and immune responses influence bacterial colonization and infection outcomes.

Genetic diversification of persistent Mycobacterium abscessus within Cystic Fibrosis patients

This study tracks genetic diversity of Mycobacterium abscessus in CF patients over time, finding non-clonal evolution and accumulation of mutations in virulence and resistance genes.

In silico secretome characterization of clinical Mycobacterium abscessus isolates provides insights into antigenic differences

The paper predicts the secretomes of M. abscessus isolates and identifies antigenic differences between subspecies and colony morphotypes.

An optimized protocol for dual RNA-Seq of human macrophages infected with Mycobacterium avium

This paper presents an optimized dual RNA-Seq protocol for human macrophages infected with Mycobacterium avium to better study host-pathogen interactions.

Who infects Whom? - Reconstructing infection chains of Mycobacterium avium ssp. paratuberculosis in an endemically infected dairy herd by use of genomic data

This study reconstructs infection chains of Mycobacterium avium ssp. paratuberculosis in a dairy herd using genomic data and demographic information to identify transmission patterns and risk factors.

Six species of non-tuberculosis mycobacteria carry non-identical 16S rRNA gene copies

The paper identifies non-identical 16S rRNA gene copies in six non-tuberculosis mycobacteria species using cloning and sequencing.

Extensive genomic diversity among Mycobacterium marinum strains revealed by whole genome sequencing

This study uses whole genome sequencing to reveal extensive genomic diversity among Mycobacterium marinum strains, suggesting they should be divided into two clusters.