Topic · Organic Chemistry · Chemistry
OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.
40 papers
José Manuel Ezquerra-Aznárez, Raquel Alonso-Román, Ainhoa Lucía, Raquel Andreu, Santiago Franco, José Antonio Aínsa, Santiago Ramón‐García
This study identifies 4H-pyran-4-ylidenes as antimicrobial compounds from an industrial chemical library active against Gram-positive bacteria, including MRSA, with low cytotoxicity.
bioRxiv · Jan 21, 2025 · PreprintMicrobiology
Lin Ruan, Cun Fan, Jingjie Chen, Yingxia Wang, Yuji Ren, Wenli Yuan, Xiaozhe Xiong, Chunming Guo
This paper evaluates a novel conjugate, COE-D8, against antibiotic-resistant UPEC, showing reduced resistance and faster bacterial elimination, but with cytotoxicity mitigated by combination with fosfomycin.
bioRxiv · Jan 19, 2025 · PreprintMicrobiology
FNU Yuqing, Shuhuan Zhang, Ruonan Peng, Justin Silva, Olivia D. Ernst, Blanca H. Lapizco‐Encinas, Rui Liu, Ke Du
This study develops a durable antimicrobial surface (DAMS) using 3D-printed microstructures and ZnO nanoflowers, showing over 90% bacterial reduction after 12 hours and effectiveness after abrasion.
Langmuir · Nov 25, 2024Peer-reviewedBioengineering
Anuja Tripathi, Julie A. Champion
The paper demonstrates that nanotextured stainless steel surfaces significantly reduce fungal adhesion by physical and chemical mechanisms, offering a sustainable alternative to antibiotics.
bioRxiv · Oct 2, 2024 · PreprintMolecular Biology
Cyrus Talebpour, Fereshteh Fani, Hossein Salimnia, Marc Ouellette, Houshang Alamdari
This study examines bacterial growth dynamics on antimicrobial surfaces, finding an inhibitory surface concentration that suppresses biofilm formation and colony growth in Escherichia coli.
PLoS ONE · Aug 19, 2024Peer-reviewedBioengineering
Elana H. Super, Si Min Lai, Urszula Cytlak, Francesco Coppola, Olivia M. Saouaf, Ye Eun Song, Kerriann M. Casey, Lauren J. Batt, Shannan-Leigh Macleod, Robert H. T. Bagley, Zarah Walsh, Petr Král, Eric Andrew Appel, Mark A. Travis, Samuel T. Jones
This paper discovers a broad-spectrum, non-toxic polymer virucide effective against multiple viruses at nanomolar concentrations, showing efficacy in a murine RSV model.
bioRxiv · Jul 10, 2024 · PreprintMicrobiology
Kholis Abdurachim Audah, G. E. Jogia, D. Kustaryono, J Amsyir, SA Amalda, Jason Darmadi, Sandiego Himawan, Syafiqah Saidin, B. A. Tejo, Cahyo Budiman, Sarah Singh, J. Thekkiniath
This study identifies THES as a non-resistant antibacterial agent that disrupts bacterial cell membranes through chelation, showing efficacy against MDR bacteria without resistance development.
bioRxiv · Jun 4, 2024 · PreprintBiochemistry
Anuja Tripathi, Jaeyoung Park, Thomas Pho, Julie A. Champion
This paper demonstrates Cu-coated nanotextured stainless steel as an antibiotic-free biocidal surface with high antibacterial activity against Gram-positive and negative bacteria.
Small · May 20, 2024Peer-reviewedMolecular Biology
The paper identifies bexarotene and sorafenib analogues as inhibitors of bacteria that grow on LB but not McConkey agar, with durable effects observed for bexarotene and JSR-N42.
bioRxiv · Apr 1, 2023 · PreprintMolecular Biology
Ilya S. Korotetskiy, Ardak B. Jumagaziyeva, Sergey V. Shilov, Tatyana V. Kuznetsova, Auyes N. Myrzabayeva, Zhanar A. Iskakbayeva, Aleksandr I. Ilin, Monique Joubert, Setshaba Taukobong, Oleg N. Reva
This study investigates the molecular effects of iodine-containing drug FS-1 on E. coli ATCC BAA-196 using transcriptomics and methylomics, revealing gene expression changes and altered methylation patterns linked to antibiotic susceptibility.
bioRxiv · May 15, 2020 · PreprintGenomics