Olivia M. Saouaf

This study shows that sustained delivery of a SARS-CoV-2 subunit vaccine in an adjuvanted hydrogel depot improves antibody responses in nonhuman primates compared to bolus vaccination.

This study develops a hydrogel-based vaccine delivery system that enhances immune responses and reduces reactogenicity in aged mice compared to Shingrix.

This paper develops a hydrogel depot system for long-acting peptide delivery, showing sustained release and improved therapeutic outcomes in rodents.

This paper develops long-acting hydrogel-based depot formulations of semaglutide and tirzepatide that maintain drug levels for over 6 weeks in a rat model, showing similar efficacy to daily injections.

This paper develops a hydrogel depot system to prolong the release of broadly neutralizing antibodies, showing improved pharmacokinetics and reduced immune cell-mediated release through co-formulation with anti-inflammatory agents.

This paper improves mRNA vaccine efficacy by creating an inflammatory immune niche via injectable hydrogel depots that recruit immune cells and enhance humoral responses.

This study shows sustained delivery of multivalent influenza vaccines via polymer-nanoparticle hydrogels enhances rapid, consistent, and broad humoral immunity against homologous and heterologous strains.

This study develops a highly extensible hydrogel bioink for high-speed 3D bioprinting, showing significant improvements in print speed and resolution.

This paper discovers a broad-spectrum, non-toxic polymer virucide effective against multiple viruses at nanomolar concentrations, showing efficacy in a murine RSV model.