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How bending scales: Geometric scaling differentially affects force responses in bending biomechanical structures

This study investigates how forces from bending structures scale with size and geometry, showing differences from spring-like structures and implications for biomechanics.

Mechanoscribed Xolography for Multiscale Mechanical Patterning of Cell-laden Hydrogels

This paper introduces a 3D bioprinting technique called Mechanoscribed Xolography to create cell-laden hydrogels with controlled mechanical heterogeneity and monitors their evolution over time.

Fast computational screening of extrusion parameters for bioprinting of skeletal myoblasts in alginate hydrogel

The paper develops a finite element-Gaussian process framework to rapidly predict optimal extrusion parameters for bioprinting skeletal myoblasts in alginate hydrogel, identifying conditions that minimize cell damage while maintaining flow rate.

Why phosphenes are not always dots: modeling the shapes elicited 1by intracortical stimulation of human V1

The paper models phosphenes elicited by intracortical stimulation in human V1, showing that electrode stimulation can produce varied shapes due to activation of multiple locations.

Enabling Spatially Resolved Gene Expression Analysis in a Multilayer Paper-Based In Vitro Tumor Model

The paper develops a workflow for spatially resolved gene expression analysis in a multilayer paper-based 3D tumor model, showing distinct spatial patterns and pharmacological responses.

Hydrogel confinement of the secreted nascent matrix imposes solid stress and mediates pathology of chondrocytes

This study shows that chondrocytes respond to solid stress from their nascent matrix in hydrogels, leading to inflammatory and migratory responses associated with osteoarthritis.

Optogenetic and sonogenetic pacing of unmodified cardiac tissue upon quick integration with specialized biological actuators

This paper demonstrates the use of optogenetic and sonogenetic biological actuators to pace unmodified cardiac tissue with high spatial precision and rapid integration.

MRI-compatible 3D Soft Carbon Neural Interface Enabled by Versatile Depth-tunable Laser Drawing

This paper introduces a 3D soft carbon neural interface fabricated via depth-tunable laser drawing, showing improved in-vitro and in-vivo performance and reduced MRI artifacts compared to 2D alternatives.

Plant cell-based 4D engineered living materials

This paper demonstrates the use of plant cells to create adaptive, programmable living materials with photosynthetic and electrochemical functionalities.

Feasibility study of fluid-structure-growth modelling in the context of endogenous tissue restoration

This study develops and validates two fluid-structure-growth models to predict long-term outcomes of vascular grafts in endogenous tissue restoration.

3D-bioprinted skeletal muscle with tailored myofibre architecture

This paper develops a 3D bioprinting method to create engineered skeletal muscle with controlled myofibre architecture, demonstrating functional tissue with various fibre orientations.

Enzymatic extracellular matrix remodeling in ex vivo slices of aged myocardium

This study shows enzymatic remodeling of aged cardiac ECM reduces stiffness but preserves contractility and some age-related transcriptional features in ex vivo myocardial slices.

Super-resolution imaging flow cytometry

This paper introduces super-resolution imaging flow cytometry (SR-IFC) to quantify organelle architecture heterogeneity at population scale, achieving sub-diffraction resolution in microbiology and immunology applications.

Decision benchmarking reveals when protein foundation models add experimental value

This paper benchmarks decision strategies for protein engineering, showing when models and measurements improve decisions based on accumulated evidence.

RhoBAST-FLIM enables high-fidelity and lifetime-assisted super-resolution RNA imaging

RhoBAST-FLIM improves RNA imaging by using fluorescence lifetime differences to enhance contrast and resolution in live cells.

Multiplexed mammalian gene control via modular splicing riboswitches

This paper introduces SpliceRACER, a modular RNA switch platform that enables multiplexed, orthogonal, and combinatorial gene regulation in mammalian cells through alternative splicing, achieving 27 discrete expression states.

Development of a Low-cost Extrusion Multi-nozzle 3D Bioprinter for Complex Constructs

This paper develops a low-cost, multi-nozzle 3D bioprinter capable of printing up to 10 different bioinks with high positional accuracy and repeatability.

BOWIe: Wireless Headstage for Optical Stimulation in Closed-Loop Optogenetics Experiments in Freely-moving Rodents

BOWIe is a wireless headstage for optogenetics in freely-moving rodents, enabling simple integration with behavioral setups and closed-loop operation.

Physics-informed neural network for predicting myocardial mechanics from in vivo physiological measurements

This paper introduces a physics-informed neural network to predict myocardial mechanics from physiological measurements, showing improved stress prediction and disease stratification in pulmonary hypertension.

Integration of In-Line Light-Mediated Cell Activation in Extrusion-Based Bioprinting: A New Biofabrication Strategy for Bone Tissue Engineering

This paper integrates broadband light stimulation into bioprinting to enhance osteogenic differentiation and vascularisation in 3D cell cultures.