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CADET improves transcriptome-wide association studies in admixed populations by integrating local ancestry and eQTL data to enhance gene expression prediction and association testing.

The paper identifies VC2 as a gene responsible for residual vicine content in low v-c faba bean cultivars, showing its role in the biosynthetic pathway and potential for marker-assisted breeding.

This study identifies Ataxin-2 as a regulator of meiotic entry in Drosophila by downregulating Dacapo, leading to timely premeiotic DNA replication and preventing genomic damage in oocytes.

This study disrupts anti-crossover mechanisms in Arabidopsis to reveal a universal crossover potential profile across sexes.

This paper introduces a probabilistic algebraic framework for modeling inheritance patterns, enabling the computation of genetic expectations and modular simulation of multi-locus inheritance processes.

The paper shows that social factors of health reduce heritability estimates for anthropometric traits when included as covariates in genetic analyses.

The paper uses extreme QTL mapping in Drosophila to identify genetic loci associated with zinc toxicity resistance, finding seven QTL and ten genes with genotype-by-treatment effects.

The paper introduces CBA, a probabilistic method to infer genetic and growth rates from cell populations, using a backbone tree and monogram to model evolutionary processes.

This study evaluates LLMs for gene-to-phenotype mapping, finding that models with dedicated databases achieve >80% accuracy and provide supporting literature.

This study examines how different TTC7A missense mutations in pediatric IBD patients lead to distinct intestinal epithelial phenotypes.

This paper develops an iPSC-derived iMSC model of Osteogenesis Imperfecta that recapitulates disease phenotypes and enables drug screening.

This paper combines eDNA and acoustic-trawl data using a Bayesian joint model to estimate fish biomass, showing eDNA suggests broader distribution and potentially higher abundance of European anchovy.

This study uses Drosophila models to identify phospholipid and sphingolipid abnormalities in peroxisomal biogenesis disorders, revealing substrate channeling effects on lipid acyl chain lengths.

The paper develops a model to predict biological age from physiological traits, identifies factors influencing aging, and links {Delta}Age to mortality risk.

The paper analyzes gene expression variation in C. elegans across strains to reveal cis and trans regulatory effects and stabilizing selection on expression levels.

This study analyzes 156 genomes from the Sarmatian period in the Carpathian Basin, revealing East Asian ancestry and two unknown migration waves, with continuity into the Hunnic period.

This paper introduces a mathematical framework to classify, quantify, and compare genetic buffering relationships between genes using a ratio scale and a novel 'parallel' model.

This paper presents a high-quality genome assembly for the sea star Linckia laevigata and describes its genomic features.

This study investigates the role of juvenile hormone degradation enzymes in Drosophila development, revealing shared and unique requirements for JHE and JHEH in regulating developmental timing and growth.

The paper generates two novel D2hgdh loss-of-function mutations in Drosophila to study D-2HG accumulation and its effects on development and metabolism.