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This study presents the first transcriptome analysis of the winter tick, identifying sex-specific gene expression and a novel doublesex-like splicing mechanism in chelicerates.

The paper identifies sex differences in cardiac metabolism, showing female hearts have higher fatty acid oxidation gene expression and energy utilization compared to male hearts.

This study shows that Pab1 in yeast primarily controls translation by blocking mRNA decapping and decay, with reduced mRNA abundance driving translational changes.

The paper analyzes genome sequences of Candida albicans isolates from APECED patients to identify genetic adaptations associated with azole resistance.

The paper develops a pan-gene catalogue for Asian cultivated rice by creating a reference panel of 16 cultivars and identifying core and cultivar-specific genes.

This study investigates the role of Spn1 in maintaining chromatin structure, showing its importance in preserving nucleosome positioning and promoter architecture in yeast.

The paper identifies and validates differentially expressed circulating miRNAs in heart failure patients with and without obesity, finding three miRNAs upregulated in both groups and associated with biological processes related to HF.

The paper integrates single-cell and bulk RNA sequencing data to identify macrophage subpopulations and functional states in Lyme arthritis, revealing biomarkers and therapeutic targets.

The paper identifies a novel double-stranded DNA virus in ants and shows its long-term co-evolution with host species through genomic and phylogenetic analysis.

This paper presents a new genome assembly for Amoebophrya sp. ex Karlodinium veneficum, revealing genomic diversity and contextual stop codon translation.

This paper develops a targeted genomic surveillance approach for insecticide resistance in malaria vectors, identifying resistance variants and demonstrating predictive modeling with high accuracy.

This study performs single-cell RNA sequencing on primary human trabecular meshwork cells in vitro to compare gene expression with in situ tissue, providing a public resource for studying cellular identity and translatability.

This study shows that mutational and clonality profiles in HGSOC are established early and remain stable through therapy resistance.

The paper shows transposons drive chromosomal speciation in Opsariichthys by enabling centromere expansion and chromosome fission, creating reproductive barriers.

The paper introduces a dimensionality reduction method to classify single-cell chromosome structures into conformational clusters, revealing that distinct morphologies influence gene function through subnuclear positioning.

The paper compares enhancer codes of cell types between mammalian neocortex and avian pallium using deep learning, finding higher divergence in excitatory neurons than other cell types.

The paper tracks the emergence and spread of a novel reassortant swine influenza virus in Denmark, highlighting its zoonotic potential and antigenic differences from human viruses.

The paper examines genomic diversity within the MDA-MB-231 breast cancer cell line across sublines, identifying intraline heterogeneity driven by single nucleotide variants and copy number alterations.

This paper compares state-space models and transformers for predicting RNA-Seq read coverage, finding Mamba-based models slightly outperform transformers in accuracy but not in downstream SNP classification.

This paper introduces DEFND-seq, a method for jointly profiling DNA and RNA from individual nuclei, enabling analysis of gene expression with copy number and SNV associations.