Economic hardship mediates differences in brain network dynamics associated with family history of substance use disorder in a sex-specific manner
Louisa Schilling, Marie Hédo, Keith Wakefield Jamison…·Amy F. Kuceyeski
363,000+ bioRxiv and medRxiv preprints, including those later published in peer-reviewed journals, across 26 biological disciplines.
Louisa Schilling, Marie Hédo, Keith Wakefield Jamison…·Amy F. Kuceyeski
Shai Berman, Amir Lawen, Sharon Xu…·Daphna Shohamy A
This study investigates how the brain retrieves taste memories from visual cues, finding that taste memory is represented in lateral parietal cortex rather than gustatory cortex.
Bruna Rabelo Ribeiro Domingues, Gabriel Santos Félix, Maria Fernanda Lucena Bezerra…·Renato Leonardo de Freitas
This review evaluates CBD's effects on rodent ASD models, finding beneficial behavioral and neurobiological outcomes but highlighting methodological limitations.
Devanshu Kaushik, Prachi Dugam, Gourav Sarkar…·Prem N. Yadav
This study shows that TGR5 agonism expands hippocampal neural stem cells, reduces senescence, and improves cognitive function in aged mice without promoting neuronal differentiation.
Kevin A. LeBlanc, Anne T.D. Lacroix, Jada A Benwell…·Heather F. Neyedli
The paper investigates how grasping is planned under target uncertainty using a GBYK paradigm and finds asymmetric interference from nontarget objects.
Daria Meshcherina, Benjamin Auffarth, Tony Lindeberg
The paper measures variability in receptive field shapes in mice, finding elongation variability exceeding measurement noise, supporting predictions from higher mammals.
郭长亮 Guo Changliang, Mian Xie, 邱国华…·Liangyi Chen
The paper introduces COMET, a lightweight head-mounted mesoscope for cortex-wide single-cell calcium imaging in freely moving mice, demonstrating its ability to capture neural activity during natural behaviors.
Eugenia Amici, Rafael Grimson, Pablo Moriña Vázquez
The paper presents an open dataset of developmental milestones for mice, rats, and humans, showing non-linear scaling between species and introducing a quarter-power transformation to improve cross-species comparability.
Juliet Jiang, Gengshuo Tian, Brent Doiron
This paper uses operator-valued free probability to analyze how global and local circuit structures affect population activity dimensionality in recurrent neural networks with heterogeneous gains.
Sir-Lord Wiafe, Najme Soleimani, Zening Fu…·Vince D. Calhoun
This study identifies a dynamic directional coordination axis in the cortical hierarchy that is selectively reorganized in schizophrenia, linked to symptoms and cognition.
Ziying Tang, James Dowsett, Paul H. Taylor…·Michael Pecka
This study investigates how agency and embodiment affect perception, metacognition, and neural processing during active sensing, finding that agency improves accuracy and neural responses while embodiment uniquely enhances confidence.
Yihan Tang, Amanda Xiao, Yufei Xiao…·Mohammad Moshahid Khan
The paper analyzes regulator activity across mouse PFF Parkinson disease models and human PD data, identifying shared transcriptional programs in dopaminergic identity, protein homeostasis, and inflammation.
Aarav Sinha, Oluwajomiloju C. Fasehun, William T. Redman
The paper investigates predictive grid cells in rodent MEC, finding they are a general feature and may shape grid cell population activity rather than requiring explicit planning.
Citlalli Vivar, Demetrio Ferro, Aaron J. Levi…·Klaus Wimmer
The paper investigates how temporal weighting of sensory evidence in decision-making is shaped by interactions between sensory and decision circuits using behavioral, neural, and computational models in macaques.
Mathieu Galerne, Eleni Siopi, Audrey Rousseaud…·Franck Oury
This study identifies PTH1R signaling in AgRP neurons as a mechanism controlling feeding behavior and nutrient partitioning through distinct kinase activation and lipophagic processes.
Lester P. Sands, Seth R. Batten, Alec E. Hartle…·Read Montague
This study measures fast dopamine transients in human olfactory epithelium during reward learning tasks and finds they shift from outcomes to cues, matching prediction error signals.
Ana Morello-Megias, Bhanu Shankar Dhulipalla, Han Ali Kahvecioglu…·Jean-Pierre Roussarie
This study creates a molecular atlas of the mouse entorhinal cortex using snRNAseq and compares it to macaque data, revealing conserved molecular patterns and gradients in neuron subtypes.
Reema Arbid, Ithai Rabinowitch
This study shows that prior high effort in C. elegans increases subsequent food approach and aversive barrier crossing, with effects lasting up to 1 hour.
Andrew H. Cooper, Paschalina Chrysostomidou, Ana Jurado Santos…·Greg A. Weir
The paper demonstrates that precision targeting of injured sensory neurons using gene therapy alleviates neuropathic pain in mice.