Discover, rate, and discuss biology preprints.

This study examines age-related changes in noise correlations in mice performing a visual decision-making task, finding regionally heterogeneous effects rather than a brain-wide shift.

This paper develops an fMRI method to measure contrast sensitivity across the visual field without requiring precise fixation, showing reliable patterns and tolerance to eye movement.

This study examines how behavioural activity affects EEG power spectrum, source localization, and global functional connectivity in freely moving rats, identifying specific frequency band changes.

This paper develops a method to align brain activity between humans and monkeys, revealing conserved visual areas and species-specific differences in higher-order processing.

The paper investigates tactile long-term memory retrieval, finding increased somatosensory cortex and hippocampal activity during successful recognition of learned vibrotactile patterns.

This study investigates the effects of modulating VIP+ neurons in mouse corticolimbic regions on anxiety, social behavior, and fear learning, finding region-specific impacts on fear learning in the mPFC.

This paper reveals that dopamine release is highly localized to synapse-like structures, challenging the idea that neuromodulators act diffusely.

This study links LDL-C to cerebral pericyte dysfunction in acute ischemic stroke through clinical and experimental evidence, showing oxidative stress and type-I interferon signaling changes.

This study identifies the role of dorsal raphe nucleus neurons in stress-induced shifts from goal-directed to habit-driven behavior using mouse models and molecular profiling.

Site-aware population GNN on ABIDE-I: cohort AUC about 0.94 (kept with site-only edges) was not reproduced by a site-prior classifier (0.506); a directed-edge support gain (+0.252) vanished when symmetrised (−0.003).

The paper shows that sensory adaptation and expectation-related signals in visual cortex are represented as distinct population dimensions, with ACC input modulating the expectation-related axis.

The paper shows that innate sensorimotor policies interact with cerebellar feedback to enable adaptive correction in zebrafish, revealing innate structure as a constraint on cerebellar adaptation.

This study shows that tFUS targeting the PCC during mindfulness training increases DMN-CEN decoupling in novices, mimicking effects seen in experienced meditators after just two weeks.

The paper demonstrates that traveling brain waves support flexible working memory by minimizing neural interference during updates, supported by both artificial neural networks and human intracranial recordings.

This paper introduces NeOPID, a framework to quantify information in brain oscillations, showing phase and amplitude co-modulations act as complementary coding channels with redundant and synergistic components.

This study shows ANGPTL7 affects immune cells in the optic nerve head, contributing to neurodegeneration in glaucoma, despite no effect on intraocular pressure.

The paper shows that a two-stage model (APE) outperforms a direct-mapping neural network in predicting limb dynamics under novel conditions by explicitly modeling equations of motion and numerical integration.

The paper trains RNNs with short-term plasticity to perform decision-making tasks, showing that evidence accumulates during activity-silent periods through synaptic efficacy changes.

This study shows that TDP-43 mutations in ALS/FTD reduce HSV-1 infection by disrupting cell-adhesion pathways and impairing viral entry.

The paper shows that humans encode sequences with order-based structure as mental programs, improving recall accuracy and predicting motor production patterns.