Discover, rate, and discuss biology preprints.

The paper develops an in situ method using OCT injection to accurately measure thoracic aortic aneurysms in mice without causing damage.

This study investigates how L-DOPA dose affects neural oscillations in LID and shows ketamine suppresses some of these signatures in specific brain regions.

This study reports a co-infection of a novel Chlamydia-like organism and Henneguya sp. in snakeskin gourami, describing their pathological effects and potential disease impact.

This study shows that Toxoplasma gondii infection reduces proliferation, neurogenesis, gliogenesis, and migration of mouse neural progenitor cells in vitro.

The paper identifies SLP2/prohibitin aggregates and PHB complex instability as key factors in CHCHD10S59L-related disease, leading to mitochondrial dysfunction and apoptosis.

This study uses transfer learning to train deep learning models for classifying poorly differentiated colorectal adenocarcinoma from whole slide images, achieving AUCs of 0.94-0.98.

This study identifies Rnd3 as a protective factor in placental mitochondria through PPARγ-UCP2 signaling, showing its role in mitigating oxidative stress in preeclampsia.

This study compares the effects of two knee instability models on cartilage and meniscus degeneration in mice, finding that reducing rotational instability suppresses cartilage degeneration.

This paper uses machine learning with polarimetric second-harmonic generation microscopy to classify breast tissue as cancerous or normal with high accuracy.

The paper uses deep learning to analyze digital pathology images and clinicopathological data to improve risk stratification for HER2-negative breast cancer patients.

This study shows that adenovirus-mediated ACE2 expression in mice causes obesity-specific morbidity, complicating research on SARS-CoV-2 pathogenesis in different nutritional states.

This study uses ribosome profiling to analyze translational regulation in Fusarium graminearum during wheat infection, revealing discordance between transcription and translation, novel ORFs, and roles for uORFs and miRNAs.

The paper surveys and detects Sri Lankan cassava mosaic virus (SLCMV) in Thailand, finding high prevalence and disease severity, with whitefly transmission and genetic similarity to known isolates.

This study shows SARS-CoV-2 infects brain pericytes in COVID-19 patients, leading to neurological symptoms via vascular inflammation and blood-brain barrier disruption.

This study identifies two human monoclonal antibodies with high neutralizing activity against tetanus neurotoxin, showing potential for both prophylaxis and therapy.

The paper evaluates lectins for anti-rabies virus activity, identifies Urtica dioica Agglutinin (UDA) as effective in preventing RABV infection in a muscle explant model.

The study examines Varroa mite prevalence and virus infection in Africanized honeybees in Colombia, finding high mite prevalence but low infestation and virus prevalence compared to other regions.

The paper shows that MUC1 preserves KIM-1's anti-inflammatory activity during kidney injury by preventing its cleavage by ADAM17.

This study examines whether accelerated growth due to SOCS2 deletion affects osteoarthritis vulnerability in mice, finding no effect on disease susceptibility despite changes in growth plate fusion.