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The paper shows iron accumulation drives fibrosis, senescence, and SASP in mice and humans, and demonstrates MRI can detect fibrotic burden.

This study shows maternal hepatocytes acquire developmental phenotypes during pregnancy, partially via YAP1, and maintain metabolic zonation independently of the Hippo/YAP1 pathway.

This study shows that circadian disruption from genetic and environmental factors causes metabolic issues by altering gut microbiome function and rhythmicity.

The paper quantifies the contributions of triceps surae and Achilles tendon to ankle impedance during postural control and finds that tendon stiffness dominates above low loads.

This study shows ADMA promotes lipid accumulation and adiposity through CaSR signaling, independent of NO, by activating mTOR and lipogenic genes.

This study identifies MafB and cMaf as transcription factors essential for neonatal gut nutrient uptake, showing their role in endo-lysosomal programs and metabolic pathway changes.

This study shows that tenotomy-induced muscle atrophy is sex-specific and not dependent on NFκB, but may involve autophagy differences between males and females.

The paper measures mitochondrial respiration in Atlantic salmon adipose tissue and links it to sex, genotype, and maturation timing.

This study investigates how the honeybee's octopaminergic system maintains thermoregulation under cold stress through steady-state equilibrium and alternative splicing.

This study compares optical tissue clearing methods to detect mesenchymal stromal cells in mouse lungs, finding that CUBIC enables direct imaging of fluorescently labeled MSCs and their interaction with host cells.

This study shows that angiogenesis occurs before myogenesis during skeletal muscle regeneration after biopsy injury, with microvessels establishing perfusion before myofibers reappear.

This study shows that regulating TAK1 activity can improve dystrophic muscle symptoms in a Duchenne muscular dystrophy mouse model.

This pilot study investigates how ovarian hormone levels affect circulating microRNA (cf-miRNA) expression across the menstrual cycle in human plasma, finding associations between cycle phases, hormones, and specific miRNAs.

This study shows that fenretinide reduces obesity and fatty liver but increases ceramides via Smpd3, worsening atherosclerosis in LDLR-/- mice.

This study identifies CD47 as a regulator of insulin secretion and islet transplant outcomes, showing that its inhibition enhances insulin release and transplant efficiency.

This study shows that encoding hunger through neuronal epigenome changes slows aging in Drosophila by altering histone acetylation and BCAA metabolism.

This study evaluates two tools for assessing frailty and health-related quality of life in companion dogs, finding they correlate with age-related decline in healthspan.

This study examines how low amplitude taVNS affects non-native speech category learning and pupillary responses in adults, finding faster learning with taVNS but no pupillary modulation.

The paper identifies Hippo kinases as inhibitors of PI3K alpha, showing epinephrine activates these kinases to suppress insulin signaling and glucose metabolism.

This study identifies sex-biased proteomic responses to TSWV infection in salivary glands of Frankliniella occidentalis, revealing differential effects on male and female proteomes and saliva composition.