Author

S. D. Pletcher

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Animal Behavior & Cognition· 1 Cell Biology· 1 Evolutionary Biology· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 3 Research Focus:chromatin & epigenetic regulation· 3 Research Focus:development & morphogenesis· 3 Assay:bulk RNA-seq· 2 Organism:Drosophila· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2

Frequent Co-Authors

Y. Lyu· 2 shared A. H. Guo· 1 shared A. N. Goldberg· 1 shared A. S. Munneke· 1 shared A.-L. Hsu· 1 shared C. A. Shaughnessy· 1 shared C. Gendron· 1 shared C. M. Gendron· 1 shared

Activity by Year

2019-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCell Biology

Y. Lyu

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Author profile →

5 papers

Recent·Most cited

Lifespan Extension in Female Mice By Early, Transient Exposure to Adult Female Olfactory Cues

M. Garratt, I. Erturk, R. Alonzo, F. Zufall, T. Leinders-Zufall, S. D. Pletcher, R. A. Miller

This study shows that exposing female mice to adult female odors during early life extends their lifespan, while male lifespan is unaffected by such odors.

bioRxiv · Oct 7, 2022Evolutionary Biology

Encoding of hunger by the neuronal epigenome slows aging in Drosophila

K. J. Weaver, R. A. Holt, E. Henry, S. D. Pletcher

This study shows that encoding hunger through neuronal epigenome changes slows aging in Drosophila by altering histone acetylation and BCAA metabolism.

bioRxiv · Jul 21, 2022 · PreprintPhysiology

IL-13-programmed airway tuft cells produce PGE2, which promotes CFTR-dependent mucociliary function

M. E. Kotas, C. M. Moore, J. G. Gurrola, S. D. Pletcher, A. N. Goldberg, R. Alvarez, S. Yamato, P. E. Bratcher, C. A. Shaughnessy, P. L. Zeitlin, I. Zhang, Y. Li, M. T. Montgomery, K. Lee, E. K. Cope, , E. D. Gordon

The paper identifies IL-13-programmed airway tuft cells that produce PGE2, which enhances CFTR-dependent mucociliary function in allergic airways.

bioRxiv · May 11, 2022Immunology

High throughput small molecule screening reveals NRF2-dependent and -independent pathways of cellular stress resistance

D. B. Lombard, W. Kohler, A. H. Guo, C. Gendron, M. Han, W. Ding, Y. Lyu, X. Li, X. Shi, Z. Nikolovska-Coleska, Y. Duan, T. Girke, A.-L. Hsu, S. D. Pletcher, R. S. Miller

This study identifies small molecules that induce cellular stress resistance against paraquat, cadmium, and methyl methanesulfonate, with some compounds activating Nrf2 signaling and others triggering inflammatory and AMPK pathways.

bioRxiv · Sep 22, 2019Cell Biology

Perception of naturally dead conspecifics impairs health and longevity through serotonin signaling in Drosophila

T. S. Chakraborty, C. M. Gendron, Y. Lyu, A. S. Munneke, M. N. DeMarco, Z. W. Hoisington, S. D. Pletcher

This study shows that Drosophila perceives dead conspecifics, which affects health and longevity through serotonin signaling.

bioRxiv · Jan 9, 2019 · PreprintAnimal Behavior & Cognition